Studies on the Classification of Streptomyces griseus Group

Studies on the biochemistry of streptomyces. III. Glucose catabolism in Streptomyces griseus.

The operation of the tricarboxylic acid cycle and fixation of CO2 in Streptomyces griseus has recently been demonstrated in a series of tracer studies, Gilmour et al. (1955); Butterworth et al. (1955). As to the nature of the pathways of glucose catabolism in this organism, the operation of the Embden-Meyerhof glycolytic scheme and the direct oxidative pathway were indicated by inhibition studi...

Studies on Streptomyces phage. I. Growth characteristics of the Streptomyces griseus host-phage system.

Within recent years, phages capable of infecting various Streptomyces species have been reported (Saudek and Colingsworth, 1947; Reilly et al., 1947; Koerber et al., 1950; Perlman et al., 1951; and Alexander and McCoy, 1956). Hoehn (1949) and subsequently Gilmour and Buthala (1950) demonstrated that streptomyces phage is indigenous to soil, the natural habitat of the host. The streptomyces host...

Oxidation of Meloxicam by Streptomyces griseus

The aim of the present investigation was to biotransform the anti-inflammatory compound meloxicam by enzymes present in whole cells of five actinomycete cultures to produce novel bioactive derivatives. Among the actinomycetes screened, Streptomyces griseus NCIM 2622 was found to possess the enzyme system(s) that oxidize meloxicam into two metabolites whereas that present in S. griseus NCIM 2623...

Studies on the nutritional requirements of Streptomyces griseus for the formation of streptomycin.

In view of the marked activity of streptomycin in vitro against a number of species of organisms relatively resistant to penicillin, such as Escherichia coli (Schatz, Bugie, and Waksman, 1944), certain of the Salmonella (Robinson, Smith, and Graessle, 1944), Klebsiella pneumoniae (Donovick, Hamre, Kavanagh, and Rake, 1945), and Mycobacterium tuberculosis (Schatz and Waksman, 1944), as well as i...

Strain Specificity and Production of Antibiotic Substances. X. Characterization and Classification of Species within the Streptomyces Griseus Group.